Abstract: According to the characteristics of oxide gold ore containing carbon and arsenic in Anhui Jixi,extracted and refined low grade gold ore with gold content of 1. 35 g/t by grinding-cyaniding leaching process. Based on the optimizing the grinding fineness,pulp concentration,leaching time,cyanide dosage and type of adjusting agent,determined the optimum leaching conditions of gold ore. When the grinding fineness is 95%,slurry concentration is 33%,extraction time is 24 h,the dosage of KCN is 5 kg/t,the dosage of NaOH is 3 kg/t and the pH value is 11. 5,the gold leaching rate can up to87. 41%,which is relatively high recovery rate.