Abstract: Safety in operation is a crucial issue of common concern of supervision department and the unit engaging in production operation,and plays an important role in promoting sustainable and healthy development of an enterprise. Through practice and field study,the plant has taken a series of measures involving 3 aspects,i. e. safety management,environmental control and educational training,to intensify the building of the safety management system,so as to ensure the safe and smooth operation of the plant.Practice shows that the safety management system adopted tallies with the actual situation of the plant and its implementation has met with marked success.